{"id":15447,"date":"2026-03-19T09:50:54","date_gmt":"2026-03-19T08:50:54","guid":{"rendered":"https:\/\/emsaquimica.com\/?p=15447"},"modified":"2026-03-19T10:25:03","modified_gmt":"2026-03-19T09:25:03","slug":"biotechnological-hair-growth-active-prolicell-malva","status":"publish","type":"post","link":"https:\/\/emsaquimica.com\/en\/2026\/03\/19\/biotechnological-hair-growth-active-prolicell-malva\/","title":{"rendered":"ProliCell\u00ae Malva: plant biotechnology to reprogram hair growth"},"content":{"rendered":"<p data-start=\"245\" data-end=\"416\">Hair loss and follicle weakening have traditionally been addressed by one main approach: stimulating hair growth. However, this approach is based on an incomplete premise.<\/p>\n<p data-start=\"418\" data-end=\"744\">Today, we know that in many cases, hair loss is not only due to a lack of stimulation, but because the hair follicle enters a \u201cbiological shutdown\u201d state, losing its natural ability to produce hair. This requires a shift in focus: moving beyond the hair fiber and addressing the condition of the scalp and the follicle itself.<\/p>\n<p data-start=\"746\" data-end=\"1018\"><a href=\"https:\/\/emsaquimica.com\/en\/productos\/prolicell-malva\/\"><strong data-start=\"746\" data-end=\"766\">ProliCell\u00ae Malva<\/strong><\/a> is a clear example of this new generation of actives. Developed by our represented company <a href=\"https:\/\/emsaquimica.com\/en\/proveedores\/actv\/\"><strong data-start=\"858\" data-end=\"880\">ACTV Biotechnology<\/strong><\/a>, it is obtained from <em data-start=\"902\" data-end=\"920\">Malva sylvestris<\/em> using a technology based on plant stem cells and extracellular vesicles enriched with small RNAs.<\/p>\n<p data-start=\"1020\" data-end=\"1172\">Rather than simply stimulating growth, <a href=\"https:\/\/emsaquimica.com\/en\/productos\/prolicell-malva\/\">ProliCell\u00ae Malva<\/a> aims to <strong data-start=\"1084\" data-end=\"1112\">reprogram the hair cycle<\/strong>, restoring the follicle\u2019s natural ability to generate hair.<\/p>\n<h4 data-start=\"1020\" data-end=\"1172\"><span style=\"text-decoration: underline;\"><span style=\"color: #62b5e5; text-decoration: underline;\">Mechanism of action on the hair follicle<\/span><\/span><\/h4>\n<p data-start=\"1228\" data-end=\"1333\">The efficacy of <a href=\"https:\/\/emsaquimica.com\/en\/productos\/prolicell-malva\/\">ProliCell\u00ae Malva<\/a> lies in its ability to act on the main mechanisms involved in hair loss:<\/p>\n<ul>\n<li data-section-id=\"8ekcuf\" data-start=\"1335\" data-end=\"1366\"><strong data-start=\"1339\" data-end=\"1366\">Hair cycle reactivation: <\/strong>it activates key growth-related pathways such as \u03b2-catenin (CTNNB1) and reduces inhibitory signals like TGF-\u03b21, which are responsible for maintaining the follicle in a resting phase. This means it does not force growth, but reactivates the follicle\u2019s natural activity.<\/li>\n<li data-section-id=\"g6joq0\" data-start=\"1637\" data-end=\"1680\"><strong data-start=\"1641\" data-end=\"1680\">Protection against hormonal factors:<\/strong> it reduces 5\u03b1-reductase activity, helping to limit the impact of DHT and protecting the follicle from progressive weakening.<\/li>\n<li data-section-id=\"10kx1fh\" data-start=\"1807\" data-end=\"1840\"><strong data-start=\"1811\" data-end=\"1840\">Improved microcirculation: <\/strong>it stimulates factors such as VEGF, promoting oxygen and nutrient supply and creating optimal conditions for stronger, more sustained hair growth.<\/li>\n<li data-section-id=\"qteubm\" data-start=\"1989\" data-end=\"2024\"><strong data-start=\"1993\" data-end=\"2024\">Scalp hydration from within: <\/strong>it increases hyaluronic acid synthesis (HAS3) and enhances water transport through AQP3 activation, improving internal hydration of the scalp.<\/li>\n<li data-section-id=\"ytlbcx\" data-start=\"2169\" data-end=\"2194\"><strong data-start=\"2173\" data-end=\"2194\">Anti-aging action: <\/strong>it promotes melanin synthesis, helping maintain the natural color of the hair and supporting an overall anti-aging approach.<\/li>\n<\/ul>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-15433\" src=\"https:\/\/emsaquimica.com\/wp-content\/uploads\/2026\/03\/Diseno-sin-titulo-3-300x81.png\" alt=\"\" width=\"515\" height=\"139\" srcset=\"https:\/\/emsaquimica.com\/wp-content\/uploads\/2026\/03\/Diseno-sin-titulo-3-300x81.png 300w, https:\/\/emsaquimica.com\/wp-content\/uploads\/2026\/03\/Diseno-sin-titulo-3-1024x276.png 1024w, https:\/\/emsaquimica.com\/wp-content\/uploads\/2026\/03\/Diseno-sin-titulo-3-768x207.png 768w, https:\/\/emsaquimica.com\/wp-content\/uploads\/2026\/03\/Diseno-sin-titulo-3-1536x415.png 1536w, https:\/\/emsaquimica.com\/wp-content\/uploads\/2026\/03\/Diseno-sin-titulo-3.png 1600w\" sizes=\"(max-width: 515px) 100vw, 515px\" \/><\/p>\n<blockquote><p><em><span class=\"TextRun SCXW212909306 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW212909306 BCX0\">ACTV Biotechnology.\u00a0<\/span><span class=\"NormalTextRun SCXW212909306 BCX0\">ProliCell<\/span><span class=\"NormalTextRun SCXW212909306 BCX0\">\u00ae Malva \u2013 Technical Data Sheet. ACTV Biotechnology<\/span><\/span><\/em><\/p><\/blockquote>\n<h4 data-section-id=\"auemvl\" data-start=\"2326\" data-end=\"2348\"><span style=\"color: #62b5e5;\"><strong><span style=\"text-decoration: underline;\">Visible results<\/span><\/strong><\/span><\/h4>\n<p data-start=\"2350\" data-end=\"2499\">The effectiveness of this approach has been confirmed in clinical studies conducted over 3 months in volunteers with alopecia or excessive hair loss:<\/p>\n<ul>\n<li data-start=\"2503\" data-end=\"2571\">Hair loss reduction of <strong data-start=\"2526\" data-end=\"2545\">73% (pull test)<\/strong> and <strong data-start=\"2550\" data-end=\"2569\">66% (wash test)<\/strong><\/li>\n<li data-start=\"2574\" data-end=\"2625\">Visible improvement in hair density and thickness<\/li>\n<li data-start=\"2628\" data-end=\"2663\">Healthier and more balanced scalp<\/li>\n<li data-start=\"2666\" data-end=\"2701\"><strong data-start=\"2666\" data-end=\"2701\">22% increase in melanin content<\/strong><\/li>\n<\/ul>\n<p data-start=\"2703\" data-end=\"2809\">Users also reported stronger, softer, and shinier hair, reflecting an overall improvement in hair quality.<\/p>\n<h4 data-section-id=\"1orkij1\" data-start=\"2816\" data-end=\"2861\"><span style=\"text-decoration: underline; color: #62b5e5;\"><strong data-start=\"2819\" data-end=\"2861\">Applications in hair care formulations<\/strong><\/span><\/h4>\n<p data-start=\"2863\" data-end=\"2972\">Thanks to its activity profile, ProliCell\u00ae Malva can be incorporated into a wide range of hair care products:<\/p>\n<ul>\n<li data-start=\"2976\" data-end=\"3001\">Anti-hair loss shampoos<\/li>\n<li data-start=\"3004\" data-end=\"3017\">Hair serums<\/li>\n<li data-start=\"3020\" data-end=\"3038\">Scalp treatments<\/li>\n<li data-start=\"3041\" data-end=\"3062\">Oils or hair creams<\/li>\n<li data-start=\"3065\" data-end=\"3076\">Hair dyes<\/li>\n<\/ul>\n<p data-start=\"3078\" data-end=\"3142\">The active is typically used at concentrations between <strong data-start=\"3133\" data-end=\"3141\">2\u20135%<\/strong>.<\/p>\n<p data-start=\"3185\" data-end=\"3346\"><a href=\"https:\/\/emsaquimica.com\/en\/productos\/prolicell-malva\/\">ProliCell\u00ae Malva<\/a> represents a new way of understanding hair care: an approach that addresses the root cause of the problem, rather than just its visible effects.<\/p>\n<h4 data-section-id=\"1wj8pjc\" data-start=\"3353\" data-end=\"3399\"><span style=\"text-decoration: underline; color: #62b5e5;\"><strong data-start=\"3356\" data-end=\"3399\">A biotechnological active for hair care<\/strong><\/span><\/h4>\n<p data-start=\"3401\" data-end=\"3528\">Plant biotechnology enables the development of ingredients capable of acting on the cellular processes involved in hair growth.<\/p>\n<p data-start=\"3530\" data-end=\"3717\"><a href=\"https:\/\/emsaquimica.com\/en\/productos\/prolicell-malva\/\">ProliCell\u00ae Malva<\/a> combines plant stem cells from <em data-start=\"3578\" data-end=\"3596\">Malva sylvestris<\/em> with extracellular vesicles enriched in small RNAs to stimulate hair follicles, reduce hair loss, and protect the scalp.<\/p>\n<p data-start=\"3719\" data-end=\"3846\">Discover more about <a href=\"https:\/\/emsaquimica.com\/en\/productos\/prolicell-malva\/\">ProliCell\u00ae Malva<\/a> and its applications in formulation by visiting our <a href=\"https:\/\/emsaquimica.com\/en\/productos\/prolicell-malva\/\">product page<\/a>.<\/p>\n<p data-start=\"3185\" data-end=\"3346\">\n","protected":false},"excerpt":{"rendered":"<p>Hair loss is not always caused by lack of stimulation, but by a \u201cswitched-off\u201d follicle. ProliCell\u00ae Malva introduces a new approach by reactivating its biological activity to restore natural hair growth from the root.<\/p>\n","protected":false},"author":12,"featured_media":15440,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[100,118,96,97],"tags":[],"class_list":["post-15447","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general-en","category-performance-chemicals-en","category-productos-en","category-representadas-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Biotechnological hair growth active | ProliCell\u00ae Malva<\/title>\n<meta name=\"description\" content=\"Discover how ProliCell\u00ae Malva acts on the hair follicle to reduce hair loss and support hair growth through plant biotechnology.\" \/>\n<meta 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